Targeting gasdermin E in neurodegenerative diseases.

Zhou, Zhi Dong; Yi, Ling Xiao; Tan, Eng King · Cell Rep Med · 2023

editorial · Level V

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Abstract

Neel et al. identified pathophysiologic clues linking gasdermin-E (GSDME) with frontotemporal dementia and amyotrophic lateral sclerosis.<sup>1</sup> Therapeutic studies targeting GSDME may provide a viable approach for neurodegenerative diseases.

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