Response to comment on 'A conserved strategy for inducing appendage regeneration in moon jellyfish, <i>Drosophila</i>, and mice'.
Where this comes from
- Record sourced from PubMed, PMID 37347515.
- Also identified by DOI 10.7554/eLife.85370 and PMC identifier 10287153.
- Licence recorded as CC BY.
- The licence permits redistribution, so the abstract is shown in full and the full text is available from the publisher.
Abstract
Previously we reported evidence that a regenerative response in the appendages of moon jellyfish, fruit flies, and mice can be promoted by nutrient modulation (Abrams et al., 2021). Sustar and Tuthill subsequently reported that they had not been able to reproduce the induced regenerative response in flies (Sustar and Tuthill, 2023). Here we discuss that differences in the amputation method, treatment concentrations, age of the animals, and stress management explain why they did not observe a regenerative response in flies. Typically, 30-50% of treated flies showed response in our assay.
Medical subject headings
- Drosophila
- Scyphozoa