Shaping the cerebral cortex by cellular crosstalk.
review · Level V
Where this comes from
- Record sourced from PubMed, PMID 37352835.
- Also identified by DOI 10.1016/j.cell.2023.05.040.
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Abstract
The cerebral cortex is the brain's outermost layer. It is responsible for processing motor and sensory information that support high-level cognitive abilities and shape personality. Its development and functional organization strongly rely on cell communication that is established via an intricate system of diffusible signals and physical contacts during development. Interfering with this cellular crosstalk can cause neurodevelopmental disorders. Here, we review how crosstalk between migrating cells and their environment influences cerebral cortex development, ranging from neurogenesis to synaptogenesis and assembly of cortical circuits.
Medical subject headings
- Cerebral Cortex
- Neurogenesis