CNS-associated macrophages shape the inflammatory response in a mouse model of Parkinson's disease.
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 37365158.
- Also identified by DOI 10.1038/s41467-023-39061-9 and PMC identifier 10293184.
- Licence recorded as CC BY.
- The licence permits redistribution, so the abstract is shown in full and the full text is available from the publisher.
Abstract
In an alpha-synuclein (α-syn) model of Parkinson’s disease (PD), Schonhoff and colleagues have shown that central nervous system (CNS)-associated macrophages (CAMs), but not microglia, potentially orchestrate CD4<sup>+</sup> T cell recruitment and mediate an α-syn-induced inflammatory makeup.
Medical subject headings
- Parkinson Disease