Inequalities in urban greenness and epigenetic aging: Different associations by race and neighborhood socioeconomic status.
prospective_cohort · Level II
Where this comes from
- Record sourced from PubMed, PMID 37379393.
- Also identified by DOI 10.1126/sciadv.adf8140 and PMC identifier 10306284.
- Licence recorded as CC BY.
- The licence permits redistribution, so the abstract is shown in full and the full text is available from the publisher.
Abstract
Slower epigenetic aging is associated with exposure to green space (greenness); however, the longitudinal relationship has not been well studied, particularly in minority groups. We investigated the association between 20-year exposure to greenness [Normalized Difference Vegetation Index (NDVI)] and epigenetic aging in a large, biracial (Black/white), U.S. urban cohort. Using generalized estimating equations adjusted for individual and neighborhood socioeconomic characteristics, greater greenness was associated with slower epigenetic aging. Black participants had less surrounding greenness and an attenuated association between greenness and epigenetic aging [β<sub>NDVI5km</sub>: -0.80, 95% confidence interval (CI): -4.75, 3.13 versus β<sub>NDVI5km</sub>: -3.03, 95% CI: -5.63, -0.43 in white participants]. Participants in disadvantaged neighborhoods showed a stronger association between greenness and epigenetic aging (β<sub>NDVI5km</sub>: -3.36, 95% CI: -6.65, -0.08 versus β<sub>NDVI5km</sub>: -1.57, 95% CI: -4.12, 0.96 in less disadvantaged). In conclusion, we found a relationship between greenness and slower epigenetic aging, and different associations by social determinants of health such as race and neighborhood socioeconomic status.
Medical subject headings
- Social Class
- Residence Characteristics