Atypical hyperplasia of the breast: Clinical cases and management strategies.

Vegunta, Suneela; Mussallem, Dawn M; Kaur, Aparna S; Pruthi, Sandhya; Klassen, Christine L · Cleve Clin J Med · 2023

review · Level V

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Abstract

Atypical hyperplasia of the breast is a histopathologic lesion identified incidentally on image-guided breast biopsy. It is associated with a substantial increase in lifetime risk for breast cancer. Clinicians should counsel women with atypical hyperplasia regarding risk-reducing strategies, which include preventive endocrine therapy options, enhanced surveillance imaging, and lifestyle modifications. In this review, we describe 5 different but common clinical case scenarios for atypical hyperplasia of the breast and review management strategies for each scenario.

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