Viral load quantitation at the point-of-care with shaken digital droplet RT-LAMP.
other · Level V
Where this comes from
- Record sourced from PubMed, PMID 37431299.
- Also identified by DOI 10.1039/d3lc00096f and PMC identifier 10368152.
- Licence recorded as CC BY-NC.
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Abstract
Viral load quantitation is useful in clinical point-of-care settings to assess the status of patients with infectious disease, track response to treatment, and estimate infectiousness. However, existing methods for quantitating viral loads are complex and difficult to integrate into these settings. Here, we describe a simple, instrument-free approach for viral load quantitation suitable for point-of-care use. We develop a shaken digital droplet assay that can quantitate SARS-CoV2 with sensitivity comparable to gold standard qPCR.
Medical subject headings
- COVID-19
- Point-of-Care Systems