Sex- and timing-specific effects of fasting and caloric restriction.

Hofer, Sebastian J; Madeo, Frank · Cell Metab · 2023

review · Level V

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Abstract

Optimizing food quantity and fasting time may improve health and lifespan. We summarize emerging knowledge on sex, age, and circadian timing as important determinants for the efficacy of dietary interventions and highlight results from Duregon et al. pointing to a favorable combination of caloric restriction (CR) and fasting in aged female mice.

Medical subject headings