Respiratory syncytial virus Prefusion F vaccine.
review · Level V
Where this comes from
- Record sourced from PubMed, PMID 37478816.
- Also identified by DOI 10.1016/j.cell.2023.05.048.
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Abstract
Respiratory syncytial virus (RSV) is the most common cause of serious respiratory infection in infants. Reinfections occur commonly, including in older adults. For six decades, effective vaccines remained elusive. Stabilization of the prefusion conformation of the RSV glycoprotein F was critical for development of effective vaccines to prevent RSV in older adults. To view this Bench to Bedside, open or download the PDF.
Medical subject headings
- Respiratory Syncytial Virus Infections
- Respiratory Syncytial Virus Vaccines
- Respiratory Syncytial Virus, Human