One antigen closer to understanding membranous nephropathy.
review · Level V
Where this comes from
- Record sourced from PubMed, PMID 37479386.
- Also identified by DOI 10.1016/j.kint.2023.05.011.
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Abstract
Membranous nephropathy is an immune-mediated kidney disease characterized by subepithelial immune deposits. Through the utilization of advanced proteomic techniques, multiple target antigens have been identified, including those associated with primary and secondary etiologies. Nonsteroidal anti-inflammatory drugs represent an important secondary cause of membranous nephropathy. In this study by Sethi et al., advanced proteomic techniques identify proprotein convertase subtilisin/kexin type 6 as a target antigen in nonsteroidal anti-inflammatory drug-associated membranous nephropathy.
Medical subject headings
- Glomerulonephritis, Membranous