Association Between Duration of SARS-CoV-2 Positivity and Long COVID.

Pozzi, Chiara; Sarti, Riccardo; Levi, Riccardo; Mollura, Maximiliano; Azzolini, Elena; Barbieri, Riccardo; Mantovani, Alberto; Rescigno, Maria · Clin Infect Dis · 2023

retrospective_cohort · Level III

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Abstract

In an observational study, we analyzed 1293 healthcare workers previously infected with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), of which 34.1% developed postacute sequelae of SARS-CoV-2 infection (also known as long COVID). Using a multivariate logistic regression model, we demonstrate that the likelihood of developing long COVID in infected individuals rises with the increasing of duration of infection and that 3 doses of the BNT162b2 vaccine are protective, even during the Omicron wave.

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