IL-17A and IL-17F in tissue homeostasis, inflammation and regeneration.

Adamopoulos, Iannis E; Kuchroo, Vijay · Nat Rev Rheumatol · 2023

review · Level V

Where this comes from

Abstract

IL-17 signalling regulates both protective and harmful immune responses; therefore, its complete inhibition can have adverse effects. Detailed consideration and fine-tuning of IL-17-inhibition strategies is needed to selectively regulate disease outcomes.

Medical subject headings