Insights into juvenile myositis via engineered muscle.

Kim, Hanna · Nat Rev Rheumatol · 2023

basic_science · Level V

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Abstract

The pathogenesis of juvenile dermatomyositis (JDM) is complex and various evidence implicate a role for type I interferons. Could the use of a bioengineered paediatric skeletal muscle model provide insight into this disease and have potential for high throughput testing of therapeutic agents?

Medical subject headings