Pancreatic acinar heterogeneity hijacks carcinogenesis and homeostasis.
editorial · Level V
Where this comes from
- Record sourced from PubMed, PMID 37541205.
- Also identified by DOI 10.1016/j.stem.2023.07.008.
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Abstract
In this issue, Jiang and colleagues employ multiple lineage-tracing approaches to elaborate on the role of Tff2+ transit-amplifying progenitor cells in the pancreatic acinar compartment of mice. This work provides insights into the steady-state homeostasis and tumor-suppressive features of certain progenitor cells and presents findings on acinar cell heterogeneity.
Medical subject headings
- Acinar Cells
- Pancreatic Neoplasms