First Known Human Death After Infection With the Avian Influenza A/H3N8 Virus: Guangdong Province, China, March 2023.

Zhuang, Yali; Wang, Man; Liang, Lijun; Mao, Yunxia; Wang, Kaibin; Yang, Shuhuan; Deng, Aiping; Zeng, Kewen et al. · Clin Infect Dis · 2024

case_report · Level V

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Abstract

Here, we report on a case of human infection with the H3N8 avian influenza virus. The patient had multiple myeloma and died of severe infection. Genome analysis showed multiple gene mutations and reassortments without mammalian-adaptive mutations. This suggests that avian influenza (A/H3N8) virus infection could be lethal for immunocompromised persons.

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