Identifying Effective Durations of Antibiotic Therapy for the Treatment of Carbapenem-resistant Enterobacterales Bloodstream Infections: A Multicenter Observational Study.

Soto, Caitlin L; Hsu, Alice J; Lee, Jae Hyoung; Dzintars, Kathryn; Choudhury, Rebecca; Jenkins, Timothy C; McCreary, Erin K; Quartuccio, Katelyn S et al. · Clin Infect Dis · 2024

retrospective_cohort · Level III

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Abstract

In a propensity-score-weighted cohort of 183 adults with carbapenem-resistant Enterobacterales bacteremia at 24 US hospitals, patients receiving short courses of active therapy (7-10 days, median 9 days) experienced similar odds of recurrent bacteremia or death within 30 days as those receiving prolonged courses of active therapy (14-21 days, median 14 days).

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