Role of IL-6 and IL-6 targeted therapy in systemic lupus erythematosus.
review · Level V
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- Record sourced from PubMed, PMID 37594751.
- Also identified by DOI 10.1093/rheumatology/kead416.
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Abstract
Interleukin-6 (IL-6) is one of the cytokines implicated in murine and human SLE. Only a few small studies have investigated IL-6 inhibition in human SLE. Currently, there are no studies registered in clinicaltrials.gov to assess the IL-6 targeted therapy in SLE, yet its role in the future remains to be defined. This narrative review analyses these and potential areas of future studies with IL-6 targeted therapy in SLE.
Medical subject headings
- Interleukin-6
- Lupus Erythematosus, Systemic