Finding the right context of use for molecular transplant diagnostics in kidney allograft biopsies.
editorial · Level V
Where this comes from
- Record sourced from PubMed, PMID 37599015.
- Also identified by DOI 10.1016/j.kint.2023.06.010.
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Abstract
Biopsy-based molecular diagnostics holds promise to increase diagnostic precision. In this issue of Kidney International, Beadle et al. describe a molecular classifier derived from the Banff Human Organ Transplant panel. This new molecular test specifically identifies biopsies associated with higher risk for allograft failure showing microvascular inflammation, but not considered diagnostic for antibody-mediated rejection by current Banff rules. This study marks a milestone toward defining a valuable context for use for biopsy-based molecular transplant diagnostics.
Medical subject headings
- Pathology, Molecular
- Kidney