Haunting innate immune memories of COVID-19.
editorial · Level V
Where this comes from
- Record sourced from PubMed, PMID 37657416.
- Also identified by DOI 10.1016/j.cell.2023.07.033.
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Abstract
In addition to acute hyperinflammatory responses, SARS-CoV-2 infections can have long-term effects on our immune system leading to, for example, post-acute sequelae of COVID-19 (PASC). In this issue of Cell, Cheong et al. show that severe infections via IL-6 induce persistent epigenetic signatures in hemopoietic stem cells and their myeloid progenitors associated with increased inflammatory potential.
Medical subject headings
- COVID-19
- Post-Acute COVID-19 Syndrome