Pre-extensively Drug-Resistant Congenital Tuberculosis in an Extremely Premature Baby.

Boast, Alison; How, Jeu Ann; Lau, Charis; Sett, Arun; Gilby, Damien; Burke, Andrew; McWhinney, Brett; Wright, Connor et al. · Clin Infect Dis · 2024

case_report · Level V

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Abstract

We describe a case of congenital tuberculosis in an extremely premature baby, with rapid molecular detection of a pre-extensively drug-resistant (XDR) pattern of drug resistance. The baby was treated successfully with a regimen including bedaquline and delamanid, drugs not previously described in the treatment of congenital tuberculosis (TB).

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