Visualization of Thromboinflammation by 18F-DPA-714 PET in a Stroke Patient.

Lin, Qianqian; Wang, Youliang; Zhao, Wenlong; Yao, Shaobo · Clin Nucl Med · 2023

case_report · Level V

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Abstract

A 44-year-old man who presented with progressive right limb weakness was diagnosed with ischemic stroke. He was referred for 18F-DPA-714 PET/CT for evaluation of the disease. 18F-DPA-714 PET/CT showed increased uptake of the intracranial thrombus. This DPA-714-avid thrombus highly suggested the involvement of immune cells in the extension of the clot resulting in neurological deterioration. This present case suggested that 18F-DPA-714 PET might be a promising tracer in visualizing thromboinflammation in vivo.

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