Approach to the Patient: Hormonal Therapy in Transgender Adults With Complex Medical Histories.

Iwamoto, Sean J; Rothman, Micol S; T'Sjoen, Guy; Defreyne, Justine · J Clin Endocrinol Metab · 2024

case_series · Level IV

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Abstract

While endocrinologists continue to initiate gender-affirming hormone therapy (GAHT) in healthy transgender and gender diverse (TGD) patients, they may also encounter more TGD patients in their clinics with complex medical histories that influence the patient-provider shared decision-making process for initiating or continuing GAHT. The purpose of this Approach to the Patient article is to describe management considerations in 2 adults with thromboembolic disease and 2 adults with low bone mineral density in the setting of feminizing and masculinizing GAHT.

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