Glioma Response to IDH Inhibition: Real-World Experience.

Lukas, Rimas V; Horbinski, Craig · Clin Cancer Res · 2023

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Abstract

Treatment of IDH-mutated non-enhancing grade 2 and 3 diffuse gliomas with ivosidenib leads to reduction of tumor size when assessed via volumetric MRI. Isocitrate dehydrogenase inhibition has a therapeutic benefit in patients with these tumors. See related article by Kamson et al., p. 4863.

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