Heterotopic respiratory mucosa as a potential source of ectopic Sonic hedgehog (SHH) in the development of complex radial polydactyly and ulnar dimelia.

Habenicht, Rolf; Mann, Max; Huelsemann, Wiebke; Pira, Charmaine U; Oberg, Kerby C · J Hand Surg Eur Vol · 2023

case_series · Level IV

Where this comes from

Abstract

We report eight cases of complex radial polydactyly and/or ulnar dimelia each with a fistulous lesion of heterotopic respiratory mucosa in radial-anterior skin ranging from shoulder to wrist. Although speculative, the coincidence of these rare conditions suggests a mechanistic relationship.

Medical subject headings

Anatomy