Perfusion estimation using synthetic MRI-based measurements and a porous media flow model.

Lorentzen, Rolf Johan; Nævdal, Geir; Sævareid, Ove; Hodneland, Erlend; Hanson, Erik Andreas; Munthe-Kaas, Antonella · PLoS Comput Biol · 2023

basic_science · Level V

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Abstract

The measurement of perfusion and filtration of blood in biological tissue give rise to important clinical parameters used in diagnosis, follow-up, and therapy. In this paper, we address techniques for perfusion analysis using processed contrast agent concentration data from dynamic MRI acquisitions. A new methodology for analysis is evaluated and verified using synthetic data generated on a tissue geometry.

Medical subject headings