Death-seq and ye shall find: A novel screening strategy for dying cells.
Level V
Where this comes from
- Record sourced from PubMed, PMID 37793342.
- Also identified by DOI 10.1016/j.cmet.2023.09.003.
- No licence information is recorded for this record.
- Because redistribution is not established, this page shows the abstract only. Follow the links below for the full text.
Abstract
Killing senescent cells to improve health-span holds great promise. However, screening for senescence-regulating genes and molecules is challenging because these cells do not proliferate. In this issue, Colville and Liu et al. develop Death-seq, a positive selection screening tool that overcomes this hurdle to offer broad genetic and pharmacological utility.
Medical subject headings
- Apoptosis
- Cellular Senescence