Microbial-host isozyme: A novel target in "drug the bug" strategies for diabetes.

Wu, Guojun; Zhao, Naisi; Zhao, Liping · Cell Metab · 2023

Level V

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Abstract

The role of the gut microbiome in metabolic diseases, such as diabetes, has emerged as a pivotal area of medical research. Wang et al.'s recent work reported that a gut bacteria-derived microbial-host isozyme, mimicking a human enzyme responsible for blood glucose regulation, can significantly impact the efficacy of diabetes medications.

Medical subject headings