She didn't start the fire: Mammary duct epithelial cells suppress adipocyte thermogenesis.
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 37793344.
- Also identified by DOI 10.1016/j.cmet.2023.09.007.
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Abstract
Male and female mice display highly divergent responses to cold-induced thermogenic beiging of subcutaneous adipose tissues. Recently in Nature, Patel et al. showed that mammary duct epithelial cells respond to cold-induced sympathetic activity, triggering the secretion of lipocalin 2 (LCN2) to inhibit thermogenic differentiation of adjacent mammary adipocytes.
Medical subject headings
- Adipocytes
- Thermogenesis