Seed Becoming Soil: A New Paradigm of the Ewing Sarcoma Tumor Microenvironment.
editorial · Level V
Where this comes from
- Record sourced from PubMed, PMID 37796143.
- Also identified by DOI 10.1158/1078-0432.CCR-23-2259 and PMC identifier 10873080.
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Abstract
Cells in the tumor microenvironment, including cancer-associated fibroblasts (CAF), contribute to tumor growth and immune evasion. A recent study of Ewing sarcoma identified "CAF-like" tumor cells that mimic the protumorigenic features of CAFs. These findings highlight the role of cell plasticity in tumor growth. See related article by Wrenn et al., p. 5140.
Medical subject headings
- Sarcoma, Ewing
- Cancer-Associated Fibroblasts