Fishing for "complements" with vascular organoid models of microvascular disease.
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 37802032.
- Also identified by DOI 10.1016/j.stem.2023.09.004.
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Abstract
In this issue of Cell Stem Cell, Kawakami et al. develop a SARS-CoV-2 infection-competent, progenitor-derived, human vascular organoid model and uncover a role for complement factor D (CFD) in mediating microvascular immunothrombosis. This model may be applied to conditions where microvascular disease plays a major pathogenic role.
Medical subject headings
- COVID-19