Seizing hope: Advancing cell therapy for pharmaco-resistant epilepsy toward the clinic.

Beltrán Arranz, Ana; Berninger, Benedikt · Cell Stem Cell · 2023

editorial · Level V

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Abstract

In this issue of Cell Stem Cell, Bershteyn et al.<sup>1</sup> developed a human interneuron cell therapy that reduced spontaneous seizure activity in a mouse model of mesial temporal lobe epilepsy (MTLE). The data presented here support an ongoing phase 1/2 clinical trial for the treatment of pharmaco-resistant epilepsy in patients.

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