Sex differences in a murine model of asthma are time and tissue compartment dependent.

Chiarella, Sergio E; Cuervo-Pardo, Lyda; Coden, Mackenzie E; Jeong, Brian M; Doan, Ton C; Connelly, Andrew R; Rodriguez, Raul I; Queener, Ashley M et al. · PLoS One · 2023

basic_science · Level V

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Abstract

Sexual dimorphism in lung inflammation is both time and tissue compartment dependent. Spatiotemporal variability in sex differences in a murine model of asthma must be accounted for when planning experiments to model the sex bias in allergic inflammation.

Medical subject headings