Frequency and Significance of Hepatic Involvement in New-Onset Giant Cell Arteritis: A Study of 514 Patients.
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- Record sourced from PubMed, PMID 37839813.
- Also identified by DOI 10.3899/jrheum.2023-0358.
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Abstract
Abnormalities of liver function in giant cell arteritis (GCA) have long been described<sup>1</sup> and are present at the acute phase of the disease in 30% to 60% of cases.<sup>2-4</sup> Hepatic involvement is mostly anicteric cholestasis (eg, elevated alkaline phosphatase [ALP] and gamma-glutamyl transferase [GGT]), and, more rarely, cytolytic hepatitis (eg, elevated aspartate aminotransferase [AST] and/or alanine aminotransferase [ALT]).