Poly(ADP-ribose) Polymerase Inhibitor Combinations in First-Line Metastatic Castration-Resistant Prostate Cancer: Increasing Toxicity With Unclear Benefits.

Madan, Ravi A; Karzai, Fatima; VanderWeele, David J; Cheng, Heather H; de Bono, Johann S · J Clin Oncol · 2023

editorial · Level V

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Abstract

Positive phase III trials are not truly practice changing if they do not accurately inform on the best options for patients

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