Moving closer towards a comprehensive view of tumor biology and microarchitecture using spatial transcriptomics.
Where this comes from
- Record sourced from PubMed, PMID 37919364.
- Also identified by DOI 10.1038/s41467-023-42960-6 and PMC identifier 10622517.
- Licence recorded as CC BY.
- The licence permits redistribution, so the abstract is shown in full and the full text is available from the publisher.
Abstract
Spatial transcriptomic profiling of cancer has enabled spatial delineation of malignant transcriptional heterogeneity, intercellular communication, and organization of microanatomical structures within the tumor microenvironment. This technical breakthrough paves the way for the development of precision diagnostic methods and targeted therapies.
Medical subject headings
- Transcriptome
- Neoplasms