In low-risk penicillin allergies, direct oral challenge was noninferior to skin testing followed by oral challenge.

Aung, KoKo; Htay, Thwe · Ann Intern Med · 2023

rct · Level II

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Abstract

Copaescu AM, Vogrin S, James F, et al. <b>Efficacy of a clinical decision rule to enable direct oral challenge in patients with low-risk penicillin allergy: the PALACE randomized clinical trial.</b> JAMA Intern Med. 2023;183:944-952. 37459086.

Medical subject headings