Immunological drivers of amyotrophic lateral sclerosis.
review · Level V
Where this comes from
- Record sourced from PubMed, PMID 37939160.
- Also identified by DOI 10.1126/scitranslmed.adj9332.
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Abstract
Amyotrophic lateral sclerosis (ALS), a devastating motor neuron disease involving complex genetic and environmental factors, is associated with neuroinflammation. Preclinical and clinical studies support immune system involvement in ALS pathogenesis, thereby spurring investigations into potential pathogenic mechanisms, immune response biomarkers, and ALS therapeutics.
Medical subject headings
- Amyotrophic Lateral Sclerosis