Colonic macrophages eat and feed.

Van den Bossche, Jan · Cell Metab · 2023

editorial · Level V

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Abstract

Macrophages not only secure host defense via phagocytosis but also play a key role in tissue homeostasis. A comprehensive study by Fritsch et al. reveals a novel mechanism by which macrophages in the colon deliver polyamines to epithelial cells to support self-renewal of the epithelium during periods of high proliferation.

Medical subject headings