Rebound of COVID-19 With Nirmatrelvir-Ritonavir Antiviral Therapy.

Cohen, Myron S; Brown, Elizabeth R · Ann Intern Med · 2023

other · Level V

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Abstract

In their article, Edelstein and colleagues provide the results of an observational study of virologic response in patients who received treatment with nirmatrelvir–ritonavir (N-R) versus those who received no COVID-19 therapy. The editorialists discuss the findings and emphasize the need for further consideration of the dosage, timing, and duration of treatment to inform optimal use of N-R.

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