Incidental Detection of 68 Ga-DOTA-RGD-2 Uptake in Uterine Fibroid.
case_report · Level V
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- Record sourced from PubMed, PMID 37976530.
- Also identified by DOI 10.1097/RLU.0000000000004942.
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Abstract
Uterine fibroids are benign tumors originating from the smooth muscle cells of the myometrium seen in approximately 20%-50% of women of reproductive age. The Arg-Gly-Asp (RGD) binds to αvβ3 integrin expressed on the surface of angiogenic blood vessels or tumor cells. 18 F-FDG PET/CT has been used to evaluate uterine fibroids, with moderate 18 F-FDG uptake. However, angiogenesis imaging in uterine fibroids has not been evaluated. The present case presents a rare finding of RGD uptake in the uterine fibroid on 68 Ga-DOTA-RGD-2 PET/CT in a patient who underwent angiogenesis imaging for left ankle joint pain and swelling.
Medical subject headings
- Positron Emission Tomography Computed Tomography
- Leiomyoma