The aberrant glycolysis in kidney proximal tubule: potential therapeutic target for DKD.
review · Level V
Where this comes from
- Record sourced from PubMed, PMID 37981426.
- Also identified by DOI 10.1016/j.kint.2023.09.019.
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Abstract
The presence of glycolysis in kidney proximal tubule has been long debated. However, recent reports suggest that aberrant glycolysis is induced in pathologic conditions and may play a critical role in kidney damage. Azushima et al. provided additional evidence that the accumulation of glycolysis-derived lactate could be the clue to understanding the pathogenesis of diabetic kidney disease.
Medical subject headings
- Kidney Tubules
- Kidney