Staphylococcus scratches its itch.
editorial · Level V
Where this comes from
- Record sourced from PubMed, PMID 37995654.
- Also identified by DOI 10.1016/j.cell.2023.10.027.
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Abstract
Itch exacerbates infection and inflammation-associated skin pathology. In this issue of Cell, Deng et al. identify a V8 protease released by Staphylococcus aureus triggering itch via neuronal protease-activated receptor 1. In so doing, they uncover profound consequences of microbial neurosensory modulation and the ensuing scratch-induced tissue damage that potentiates infection.
Medical subject headings
- Pruritus
- Staphylococcus aureus
- Staphylococcal Infections