Durability of Cross-Neutralizing Antibodies 5.5 Months After Bivalent Coronavirus Disease 2019 Vaccine Booster.

Rössler, Annika; Knabl, Ludwig; Netzl, Antonia; Bante, David; Borena, Wegene; von Laer, Dorothee; Smith, Derek J; Kimpel, Janine · J Infect Dis · 2024

case_series · Level IV

Where this comes from

Abstract

We analyzed neutralizing antibodies in samples from ancestral + BA.1 and ancestral + BA.4/5 boosted individuals, collected around 5.5 months after booster. Titers of neutralizing antibodies generally decreased compared to a time point early after the bivalent booster immunization. This was more pronounced for individuals without infection history and for recently emerged Omicron variants.

Medical subject headings