Multisite Mpox Infection and Viral Dynamics Among Persons With HIV in Metro Atlanta.
case_series · Level IV
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- Record sourced from PubMed, PMID 38019187.
- Also identified by DOI 10.1093/infdis/jiad530 and PMC identifier 10965212.
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Abstract
The 2022 mpox outbreak primarily involved sexual transmission among men who have sex with men and disproportionately affected persons with human immunodeficiency virus (HIV). We examined viral dynamics and clinical features in a cohort evaluated for mpox infection at a comprehensive HIV clinic in Atlanta, Georgia. Viral DNA was found in 8 oropharyngeal and 5 anorectal specimens among 10 mpox cases confirmed by lesion swab polymerase chain reaction. Within-participant anatomic site of lowest cycle threshold (Ct) value varied, and lower Ct values were found in oropharyngeal and anorectal swabs when corresponding symptoms were present. This provides insight into mpox infection across multiple anatomic sites among people with HIV.
Medical subject headings
- Mpox, Monkeypox
- Sexual and Gender Minorities
- HIV Infections