Henoch-Schönlein purpura in the setting of COVID-19 infection: Two pediatrics cases and review of the literature.
case_series · Level IV
Where this comes from
- Record sourced from PubMed, PMID 38024921.
- Also identified by DOI 10.4103/jfmpc.jfmpc_26_23 and PMC identifier 10657077.
- Licence recorded as CC BY-NC-SA.
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Abstract
Henoch-Schönlein purpura (HSP) is the most common systemic vasculitis in children, often following a viral infection. Various types of rashes attributed to COVID-19 infection have been described in the literature; however, HSP has rarely been reported. We report two children with HSP associated with acute COVID-19 infection with a review of the available literature. We highlight the clinical presentation, medical management, outcome and age-related difference of reported patients. A limitation of this article is the retrospective nature, limiting full patient history and associated conditions. The findings of this review show that HSP in the setting of COVID-19 is more common in children than adults, with a male predominance, involving various body systems creating a constellation of presentations. Given that HSP can have long-term morbidity from renal disease if untreated, this review may help guide the practitioner's approach to HSP and recognition in the setting of COVID-19 infection.