Partial cellular reprogramming: A deep dive into an emerging rejuvenation technology.
review · Level V
Where this comes from
- Record sourced from PubMed, PMID 38040663.
- Also identified by DOI 10.1111/acel.14039 and PMC identifier 10861195.
- Licence recorded as CC BY.
- The licence permits redistribution, so the abstract is shown in full and the full text is available from the publisher.
Abstract
Aging and age-associated disease are a major medical and societal burden in need of effective treatments. Cellular reprogramming is a biological process capable of modulating cell fate and cellular age. Harnessing the rejuvenating benefits without altering cell identity via partial cellular reprogramming has emerged as a novel translational strategy with therapeutic potential and strong commercial interests. Here, we explore the aging-related benefits of partial cellular reprogramming while examining limitations and future directions for the field.
Medical subject headings
- Rejuvenation
- Cellular Reprogramming