Monitoring of First-line Drug Resistance Mutations Outside the Scope of Xpert MTB/RIF Ultra is Needed for Successful Control of DR-TB in Southern Mozambique.
cross_sectional · Level IV
Where this comes from
- Record sourced from PubMed, PMID 38048599.
- Also identified by DOI 10.1093/cid/ciad684 and PMC identifier 11006097.
- Licence recorded as CC BY.
- The licence permits redistribution, so the abstract is shown in full and the full text is available from the publisher.
Abstract
Multidrug-resistant(MDR) tuberculosis in Southern Africa is of great concern, exacerbated by the spread of a clone harboring a mutation missed by Xpert Ultra. In Southern Mozambique, the presence of such mutation and rising cases of non-MDR isoniazid resistance highlights the need to ensure accurate detection of antimicrobial-resistance in the country.
Medical subject headings
- Mycobacterium tuberculosis
- Tuberculosis, Multidrug-Resistant