Using the PharmCAT tool for Pharmacogenetic clinical decision support.
Where this comes from
- Record sourced from PubMed, PMID 38055839.
- Also identified by DOI 10.1093/bib/bbad452 and PMC identifier 10699732.
- Licence recorded as CC BY.
- The licence permits redistribution, so the abstract is shown in full and the full text is available from the publisher.
Abstract
Here, we will provide our insights into the usage of PharmCAT as part of a pharmacogenetic clinical decision support pipeline, which addresses the challenges in mapping clinical dosing guidelines to variants to be extracted from genetic datasets. After a general outline of pharmacogenetics, we describe some features of PharmCAT and how we integrated it into a pharmacogenetic clinical decision support system within a clinical information system. We conclude with promising developments regarding future PharmCAT releases.
Medical subject headings
- Pharmacogenetics
- Decision Support Systems, Clinical