Breathing room: Toward next-generation tracheal engineering.

Dumas, Alexandra A; Friedman, Ryan M; Smith, Kyra W Y; Gottardi, Riccardo · Cell Stem Cell · 2023

basic_science · Level V

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Abstract

The creation of an engineered trachea with robust phenotype and sufficient mechanical properties for clinical application remains a challenge. In their work, Tang et al.<sup>1</sup> propose a stacked approach of alternating cartilaginous and fibrous rings to form a tracheal segment, which integrated and retain patency in rabbits for 8 weeks.

Medical subject headings