Late Subacute Cerebral Hematoma Mimicking a Metastasis on PSMA PET/CT.

Vaz, Nuno; Dietsche, Eric; Mooney, Michael A; Choudhury, Atish D; Jacene, Heather A · Clin Nucl Med · 2024

case_report · Level V

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Abstract

A 64-year-old man with history of prostate cancer was found to have rising prostate-specific antigen after radical prostatectomy. 18 F-DCFPyL PET/CT demonstrated a prostate-specific membrane antigen-avid brain lesion in the left frontal lobe and no other findings to account for rising prostate-specific antigen. Brain MRI demonstrated a small intraparenchymal hematoma with late subacute features in this location. The patient reported a seizure 3 weeks before but was otherwise asymptomatic, and neurologic examination was normal. Follow-up MRI demonstrated gradual decrease in size of the hematoma without treatment.

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